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U-GEMMs

About 42,406 results
Mice

R26-CAG-LSL-zsGreen

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-zsGreen)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200045

These mice harbor a CAG-LSL-zsGreen-polyA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Glp1r-IRES-Cre

Strain Name：C57BL/6Smoc-Glp1rem1(IRES-iCre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200134

A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site.

Mice

hAPOE4

Strain Name：C57BL/6Smoc-Apoetm2(hAPOE4)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190002

This APOE4 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE4 corresponding sequence by homologous recombination.

Mice

Cd2-2A-CreERT2

Strain Name：C57BL/6Smoc-Cd2em1(2A-CreERT2-WPRE-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-18017

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Mice

hCD19/hCD3E

Strain Name：C57BL/6Smoc-Cd19em1(hCD19)Cd3eem1(hCD3E)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190027

This CD19 and CD3E double knockin strain is established by crossing CD19-HU and CD3E-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hB7H4(2)

Strain Name：C57BL/6Smoc-Vtcn1em2(hVTCN1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190075

Extracellular domain of mouse Vtcn1 gene was replaced by human VTCN1 gene. While hB7H4(Stock No.NM-HU-190004) mice function similarly to hB7H4(2) mice,for more detailed information please contact our technical advisor.

Mice

Cd19-Cre-IRES-tdTomato

Strain Name：C57BL/6Smoc-Cd19em1(iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200061

A iCre-FRT-IRES-tdTomato-FRT-Wpre-polyA expression cassette was knocked into the Cd19 gene.

Mice

H11-CAG-LSL-ZsGreen-CAG-RSR-tdTomato

Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200319

A CAG-LSL-ZsGreen-wpre-pA-CAG-RSR-tdTomato-wpre-pA expression cassette was knocked into the H11 locus.

Mice

hTROP2

Strain Name：C57BL/6Smoc-Tacstd2em(hTACSTD2)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-215022

The endogenous mice Tacstd2 gene was replaced by human TACSTD2 gene.

Mice

hAPOE3

Strain Name：C57BL/6Smoc-Apoetm3(hAPOE3)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190003

This APOE3 humanized mouse model was established by replacing the mouse Apoe gene coding exons and introns with the human APOE3 corresponding sequence by homologous recombination.

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