Welcome to Advanced Search

U-GEMMs

About 42,406 results
Mice

hTLR9/hOX40

Strain Name：C57BL/6Smoc-Tlr9tm1(hTLR9)Tnfrsf4em3(hTNFRSF4)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190024

This TLR9 and OX40 double knockin strain is established by crossing TLR9-HU and OX40-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Mice

hDDR1

Strain Name：C57BL/6Smoc-Ddr1tm1(hDDR1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225086

The endogenous mouse Ddr1 gene was replaced by human DDR1 gene.

Mice

hPSGL-1

Strain Name：C57BL/6Smoc-Selplgem1(hSELPLG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00046

The endogenous mouse Selplg gene was replaced by human SELPLG gene.

Mice

Ctsk-2A-Cre

Strain Name：C57BL/6Smoc-Ctskem1(2A-Cre-Wpre-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190019

The 2A-Cre-Wpre-polyA cassette is inserted before 3'UTR region of Ctsk gene.

Mice

Alb-DreERT2

Strain Name：C57BL/6Smoc-Albem1(Kozak-DreERT2-WPRE-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200076

A Kozak-DreERT2-WPRE-pA expression cassette was knocked into the Alb gene start codon site.

Mice

hCD80

Strain Name：C57BL/6Smoc-Cd80em1(hCD80) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00074

The endogenous mouse Cd80 gene was replaced by human CD80 gene .

Mice

Il17a-Cre

Strain Name：C57BL/6Smoc-Il17aem1(iCre-polyA(SV40))Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200137

A iCre-polyA expression cassette was knocked into the Il17a gene start codon site. This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying autoimmune inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis.

Mice

Il11-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il11em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00036

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il11.

Mice

hDLL3

Strain Name：C57BL/6Smoc-Dll3em1(hDLL3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200231

The endogenous mice Dll3 gene was replaced by human DLL3 gene.

Mice

hPVR

Strain Name：C57BL/6Smoc-Pvrtm1(hPVR)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190012

The endogenous mouse Pvr gene was replaced by human PVR gene.

Email Back to top