Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Strain Name：C57BL/6Smoc-Lyz1em1(2A-DreERT2)Smoc Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190033
A 2A-DreERT2 expression cassette was knocked into the Lyz1 gene stop codon site.
Strain Name：C57BL/6Smoc-Aadacl3em1Smoc Strain State：Developing | Cat. NO.：TBD
Exon 2 of Aadacl3 gene was deleted to generate Aadacl3 knockout mice.
Strain Name：NOD.Cg-PrkdcscidIl2rgem1Csf1tm2(hCSF1)Smoc Strain State：Repository Live | Cat. NO.：NM-HU-220311
The endogenous mouse Csf1 gene was replaced by human CSF1 gene.
Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd40em1(hCD40)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190017
hPD-1(NM-HU-00015) was crossed with hCD40(NM-HU-00076) to generate hPD-1/hCD40.
Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-FGFR2(W290C)-IRES-Luciferase-2A-EGFP)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190080
These mice harbor a CAG-LSL-FGFR2(W290C)-IRES-Luciferase-2A-EGFP cassette in the Rosa26 locus generated by homologous recombination.
Strain Name：C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd47em1(hCD47) /Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220127
hCD3EDG(NM-HU-220120) mice were crossed with hCD47(NM-HU-00050) mice to generate hCD3EDG/hCD47 mice.
Strain Name：C57BL/6Smoc-Fbn1em1(C1041G)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-200303
These mice carry a C1041G mutation of Fbn1 gene.
Strain Name：C57BL/6Smoc-Grhprem1Smoc Strain State：Repository Live | Cat. NO.：NM-KO-210151
Exon 2-6 of Grhpr gene was deleted to generate Grhpr knockout mice.
Strain Name：C57BL/6Smoc-Aa467197em1Smoc Strain State：Developing | Cat. NO.：TBD
Exon 3 of Aa467197 gene was deleted to generate Aa467197 knockout mice.
Strain Name：C57BL/6Smoc-Sox10em(2A-Cre)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-220066
2A-Cre expression cassette was knocked into the Sox10 gene stop codon site.
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