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U-GEMMs

About 42,416 results
Mice

hPLK1

Strain Name：C57BL/6Smoc-Plk1tm1(hPLK1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225083

The endogenous mouse Plk1 gene was replaced by human PLK1 gene.

Mice

Arhgef10-KO

Strain Name：C57BL/6Smoc-Arhgef10em1Smoc
Strain State：Developing | Cat. NO.：TBD

Exon 5 of Arhgef10 gene was deleted to generate Arhgef10 knockout mice.

Mice

Chrnb2-KO

Strain Name：C57BL/6Smoc-Chrnb2em1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-2105377

Exon 2 of Chrnb2 gene was deleted to generate Chrnb2 knockout mice.

Mice

hIL4-Tg(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1Tg(hIL4)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-215004

These transgenic mice carry humanized IL4.

Mice

Aak1-Flox

Strain Name：C57BL/6Smoc-Aak1em1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of Aak1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aak1 gene.

Mice

Atp4b-IRES-CreERT2(2)

Strain Name：C57BL/6Smoc-Atp4bem2(IRES-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-210119

An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment.

Mice

Hexb-Linker-2A-CreERT2

Strain Name：C57BL/6Smoc-Hexbem1(Linker-3xFLAG-P2A-CreERT2-FRT-WPRE-pA-FRT)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-215050

Linker-3xFLAG-P2A-CreERT2-FRT-WPRE-pA-FRT expression cassette was knocked into the Hexb gene.

Mice

H2/H2-D1-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1h2em1H2-D1em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-005

Exon 1-6 of H2;H2-D1 gene was deleted to generate H2;H2-D1 knockout mice.

Mice

Pkd2l1-2A-CreERT2

Strain Name：C57BL/6Smoc-Pkd2l1em1(2A-CreERT2-Wpre-pA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200310

2A-CreERT2-Wpre-pA expression cassette was knocked into the Pkd2l1 gene stop codon site.

Mice

hPD-L1/hSIGLEC15

Strain Name：C57BL/6Smoc-Cd274em1(hCD274)Siglec15em1(hSIGLEC15)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000103

hPD-L1(NM-HU-00062) was crossed with hSIGLEC15(NM-HU-190037) to generate hPD-L1/hSIGLEC15.

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