Strain Model Specification

Abcb1a/Abcb1b-KO(FVB)

Strain Name FVB-Abcb1aem1Abcb1bem1Smoc
Catalog Number NM-KO-191211
Genetic Background FVB
Synonyms Pgp, Mdr3, P-gp, Pgy3, Abcb4, Evi32, Mdr1a, Pgy-3, mdr-3, mdr, Mdr1, Pgy1, Abcb1, Mdr1b, Pgy-1
NCBI ID 18671, 18669 ↗
MGI ID 97570, 97568 ↗
Ensembl ID ENSMUSG00000040584, ENSMUSG00000028970 ↗
Strain State Repository Live

Validation Data

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Fig1. In vivo PK profiles of Digoxin in FVB and Abcb1a/Abcb1b-KO mice (male, 6-8 weeks, n=6).