B16F10-hPD-L1

Background : B16F10

Catalog : NM-S31A-TM01

Strain Name :

B16F10-Cd274em1(hPDL1)/Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Cd274(also known as PD-l1)  gene was replaced by human PDL1 gene.<span style='color: rgb(80, 80, 80); font-family: PingFangSC-Regular, Arial, "Microsoft Yahei", "Segoe UI", Helvetica, "Hiragino Sans GB", "Heiti SC", "WenQuanYi Micro Hei", sans-serif;'> </span>

Validation Data

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Figure 1. hPDL1 expression in B16F10-hPDL1 cell lines.

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Figure 2. Tumor growth curve of B16F10-hPDL1 syngeneic model (n=5).

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Figure 3. Body weight change of B16F10-hPDL1 syngeneic model (n=5).

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Figure 4. The expression of hPDL1 in humanized modified tumors by FACS

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