Strain Model Specification

hCCR8(2)/hCTLA-4

Strain Name C57BL/6Smoc-Ccr8em3(hCCR8)Ctla4em1(hCTLA4)Smoc
Catalog Number NM-HU-220074
Genetic Background C57BL/6Smoc
Gene Symbol Ctla4,Ccr8
Synonyms Cd152, Ly-56, Ctla-4, C-C, CCR-8, CKR-8, mCCR8, Cmkbr8, CC-CKR-8, C-C CKR-8
NCBI ID 12477, 12776 ↗
MGI ID 88556, 1201402 ↗
Ensembl ID ENSMUSG00000026011, ENSMUSG00000042262 ↗
Strain State Embryo cryopreservation

Validation Data

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Fig1. Statistics of hCCR8 and hCTLA-4 expression in hCCR8(2)/hCTLA-4 dKI mice.

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Fig2. Detection of hCCR8 and CTLA-4 expression on T cells in Tumor in hCCR8(2)/hCTLA-4 dKI mice.

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Fig3. Detection of hCCR8 and hCTLA-4 expression on T cells in Spleen in hCCR8(2)/hCTLA-4 dKI mice.