Strain Model Specification

hIL23A

Strain Name C57BL/6Smoc-Il23atm3(hIL23A)Smoc
Catalog Number NM-HU-18030
Genetic Background C57BL/6Smoc
Gene Symbol Il23a
Synonyms p19, IL-23
NCBI ID 83430 ↗
MGI ID 1932410 ↗
Ensembl ID ENSMUSG00000025383 ↗
Strain State Embryo cryopreservation
Research Application Immunotherapy,Cancer research,Drug screening

Validation Data

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Fig1. Detection of hIL23 and mIL23 expression in serum by ELISA (n=2). 

Abbr. HO, homozygous; WT, wild type.

Note. hIL23A/hIL12B and C57BL/6 mice were i.p. injected with LPS.


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Fig2. In vivo efficacy evaluation of anti-IL-23 in imiquimod (IMQ)-induced psoriasis model in hIL23A mice (In collaboration with the third party).