Strain Model Specification

Lyz2-IRES-DTRGFP

Strain Name C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Smoc
Catalog Number NM-KI-190041
Genetic Background C57BL/6Smoc
Gene Symbol Lyz2
Synonyms Lys, Lysm, Lyzs, Lzm, Lzm-s1, Lzp
NCBI ID 17105 ↗
MGI ID 96897 ↗
Ensembl ID ENSMUSG00000069516 ↗
Strain State Repository Live

Validation Data

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Fig1. Analysis of GFP expression by FACS . The Lyz2-DTRGFP mouse expresses GFP on CD11b+ cells.


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Fig2. Analysis of the level of different immune cells in PBMC by FACS (See Figure 4 for details of diphtheria toxin injection). 


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Fig3. Analysis of the level of different immune cells in the spleen and transplanted tumor by FACS (See Figure 4 for details of diphtheria toxin injection). 

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Fig4. The growth of MC38 tumors in Lyz2-DTRGFP mice and C57BL/6 mice. 

Heterozygous Lyz2-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells.  The Lyz2-DTRGFP mice were injected with diphtheria toxin twice a week.

 The data is provided by Crownbio.