Lyz2-IRES-DTRGFP - Genobiotx

Gene Summary

Gene Name

Synonyms :
Lys, Lysm, Lyzs, Lzm, Lzm-s1, Lzp
NCBI ID :
17105
MGI ID :
96897
Ensembl ID :
ENSMUSG00000069516
Strain State :
活体

Model Description

A IRES-DTREGFP expression cassette was knocked into the Lyz2 gene stop codon site.

Validation Data

Fig1. Analysis of GFP expression by FACS . The Lyz2-DTRGFP mouse expresses GFP on CD11b+ cells.

Fig2. Analysis of the level of different immune cells in PBMC by FACS (See Figure 4 for details of diphtheria toxin injection).

Fig3. Analysis of the level of different immune cells in the spleen and transplanted tumor by FACS (See Figure 4 for details of diphtheria toxin injection).

Fig4. The growth of MC38 tumors in Lyz2-DTRGFP mice and C57BL/6 mice.

Heterozygous Lyz2-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells. The Lyz2-DTRGFP mice were injected with diphtheria toxin twice a week.

The data is provided by Crownbio.

Related Strains

Product

Product Catalog

Background

hIL3(NMG)

NM-NSG-007

NOD

Inquire

huHSC-(NMG)

NM-NSG-017

huHSC

Inquire

hANGPTL3(3)

NM-HU-210037

C57BL/6Smoc

Inquire

hTIM4

NM-HU-225042

C57BL/6Smoc

Inquire

hCTLA-4/hCD28(BALB/c)

NM-HU-200226

BALB/cAnSmoc

Inquire

hFCGR1A

NM-HU-2000072

C57BL/6Smoc

Inquire

hIL6

NM-HU-18017

C57BL/6Smoc

Inquire

hETAR

NM-HU-225039

C57BL/6Smoc

Inquire

hITGB8

NM-HU-225025

C57BL/6Smoc

Inquire

hFCGR3A

NM-HU-2000073

C57BL/6Smoc

Inquire

More..