Strain Model Specification

Ncr1-IRES-DTRGFP

Strain Name C57BL/6Smoc-Ncr1em1(IRES-DTREGFP)Smoc
Catalog Number NM-KI-190044
Genetic Background C57BL/6Smoc
Gene Symbol Ncr1
Synonyms Ly94, MAR1 (mouse activating receptor 1), NKp46
NCBI ID 17086 ↗
MGI ID 1336212 ↗
Ensembl ID ENSMUSG00000062524 ↗
Strain State Embryo cryopreservation

Validation Data

Heterozygous Ncr1-IRES-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells. After the tumors grew to 100 mm3, Ncr1-IRES-DTRGFP  mice were injected with Diphtheria toxin. 

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Fig1. The growth of MC38 tumors in Heterozygous Ncr1-IRES-DTRGFP mice and C57BL/6 mice. (Cooperation with CrownBio)

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Fig2. The percent of NK cell in peripheral blood of MC38 tumor-bearing Ncr1-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS.(Cooperation with CrownBio)

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Fig3. The percent of NK cell in peripheral blood of MC38 tumor-bearing Ncr1-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS.(Cooperation with CrownBio)