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Ncr1-IRES-DTRGFP

Background : C57BL/6Smoc

Catalog : NM-KI-190044

Strain Name : C57BL/6Smoc-Ncr1^{em1(IRES-DTREGFP)Smoc}

Gene Summary

Gene Name

Synonyms :
Ly94, MAR1 (mouse activating receptor 1), NKp46
NCBI ID :
17086
MGI ID :
1336212
Ensembl ID :
ENSMUSG00000062524
Strain State :
胚胎冻存

Model Description

A IRES-DTREGFP expression cassette was knocked into the Ncr1 gene stop codon site.

Validation Data

Heterozygous Ncr1-IRES-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells. After the tumors grew to 100 mm3, Ncr1-IRES-DTRGFP mice were injected with Diphtheria toxin.

Fig1. The growth of MC38 tumors in Heterozygous Ncr1-IRES-DTRGFP mice and C57BL/6 mice. (Cooperation with CrownBio)

Fig2. The percent of NK cell in peripheral blood of MC38 tumor-bearing Ncr1-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS.(Cooperation with CrownBio)

Fig3. The percent of NK cell in peripheral blood of MC38 tumor-bearing Ncr1-IRES-DTRGFP mice and C57BL/6 mice is detected by FACS.(Cooperation with CrownBio)

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