R26-CAG-LSL-hEGFR*T790M/del19-Luc-tdTomato

Background : C57BL/6Smoc

Catalog : NM-KI-190009

Strain Name : C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EGFR T790M-del19-luciferase-tdTomato)Smoc

Gene Summary

Gene Name
  • Synonyms :

    R26, ROSA26, AV258896, Gtrgeo26, Gtrosa26, Thumpd3as1

  • NCBI ID :

    14910

  • MGI ID :

    104735

  • Ensembl ID :

    ENSMUSG00000086429

  • Strain State :

    精子冻存

Model Description

A SA-2xpolyA-CAG-LSL-EGFR(T790M-del19)-IRES-luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EGFR(T790M-del19) protein.

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