R26-CreERT2

Nomenclature

C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA)Smoc

Cat. NO.

NM-KI-200041

Strain State

Repository Live

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Gene Summary

Gene Symbol
Gt(ROSA)26Sor

Synonyms

R26，ROSA26，AV258896，Gtrgeo26，Gtrosa26，Thumpd3as1

NCBI ID

14910

MGI ID

104735

Ensembl ID

ENSMUSG00000086429

Pubmed

Gt(ROSA)26Sor

Model Description

These mice harbor a SA-FRT-2xpolyA-CAG-FRT-CreERT2-Rox-WPRE-Rox-polyA cassette in the Rosa26 locus generated by homologous recombination. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in multiple tissues after tamoxifen treatment.
Research Application：Cre recombinase tool

Validation Data

creERT2-1.png

Fig1. Detection of tdTomato(red) in various tissues of R26CreERT2/+; Rosa26tdTomato/+ mice by fluorescence assay. Expression tissues include: brain, liver, stomach, thymus, pancreas, colon, heart, kidney and spleen. (For more detailed information please contact our technical advisor.) 

creERT2-2.png

Fig2. CreERT2-mediated recombination in peripheral blood of  R26CreERT2/+; Rosa26tdTomato/+ mice.

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