Dppa3-IRES-Cre

Nomenclature

C57BL/6Smoc-Dppa3em1(IRES-Cre)Smoc

Cat. NO.

NM-KI-00040

Strain State

Repository Live

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Gene Summary

Gene Symbol
Dppa3

Synonyms

PCG7; PGC7; Stella; 2410075G02Rik

NCBI ID

73708

MGI ID

1920958

Ensembl ID

ENSMUSG00000046323

Pubmed

Dppa3

Human Ortholog

DPPA3

Model Description

The IRES-Cre cassette was inserted into 3'UTR of Dppa(Stella) gene which express during embryonic development.
Research Application：Dppa3 (also known as Pgc7 or Stella) plays an important role in early embryonic development during the cleavage stage as a maternal effect gene.

Validation Data

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Fig. 1 Detection of Zsgreen(green) in various tissues of Dppa3Cre/+; Rosa26Zsgreen/+mice. Zsgreen expression can be detected in the brain, heart, lung, submandibular gland, salivary gland, stomach, kidney, pancreas, testis, epididymis, colon and spleen of Dppa3Cre/+; Rosa26Zsgreen/+mouse. (For more detailed information please contact our technical advisor.)

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Fig. 2 Cre-mediated recombination in the E14.5 Dppa3Cre/+; Rosa26tdTomato/+ mouse embryos. 

Publications

Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors
References：Nature Communications

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