Lyz2-IRES-DTRGFP - Genobiotx

Gene Summary

Gene Name

Synonyms :
Lys, Lysm, Lyzs, Lzm, Lzm-s1, Lzp
NCBI ID :
17105
MGI ID :
96897
Ensembl ID :
ENSMUSG00000069516
Strain State :
活体

Model Description

A IRES-DTREGFP expression cassette was knocked into the Lyz2 gene stop codon site.

Validation Data

Fig1. Analysis of GFP expression by FACS . The Lyz2-DTRGFP mouse expresses GFP on CD11b+ cells.

Fig2. Analysis of the level of different immune cells in PBMC by FACS (See Figure 4 for details of diphtheria toxin injection).

Fig3. Analysis of the level of different immune cells in the spleen and transplanted tumor by FACS (See Figure 4 for details of diphtheria toxin injection).

Fig4. The growth of MC38 tumors in Lyz2-DTRGFP mice and C57BL/6 mice.

Heterozygous Lyz2-DTRGFP mice and C57BL/6 mice were inoculated with MC38 colon cancer cells. The Lyz2-DTRGFP mice were injected with diphtheria toxin twice a week.

The data is provided by Crownbio.

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