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Gja1-2A-DreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-200026

Strain Name : C57BL/6Smoc-Gja1^{em1(2A-DreERT2）Smoc}

Gene Summary

Gene Name

Synonyms :
Cx43, Npm1, Cnx43, Cxnk1, Gja-1, AU042049, AW546267, Cx43alpha1, connexin43
NCBI ID :
14609
MGI ID :
95713
Ensembl ID :
ENSMUSG00000050953
Strain State :
精子冻存

Model Description

A 2A-DreERT2 expression cassette was knocked into the Gja1 gene stop codon site via CRISPR/Cas9 mediated recombination.

Validation Data

Fig.1 DreERT2-mediated recombination in the adipose tissue of Gja1^DreERT2/+；R26^tdTomato/+ mouse. TdTomato (red) expression can be detected in the adipose tissue after tamoxifen treatment. Connexin 43 (Cx43, encoded by Gja1, green) is a cell-cell communication gap junction protein expressed in adipose tissue. (Documented in the following reference.)

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