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hCCR5

Background : C57BL/6Smoc

Catalog : NM-HU-2000065

Strain Name : C57BL/6Smoc-Ccr5^{tm1(hCCR5)/Smoc}

Gene Summary

Gene Name

Synonyms :
AM4-7, CD195, Cmkbr5
NCBI ID :
12774
MGI ID :
107182
Ensembl ID :
ENSMUSG00000079227
Strain State :
胚胎冻存

Model Description

The endogenous mouse Ccr5 gene was replaced by human CCR5 gene.

Validation Data

NM-HU-2000065 hCCR5.png

Fig1. Analysis of CCR5 gene expression in the spleen by RT-PCR.

Mouse Ccr5 mRNA was detectable by P1/2(869bp), human CCR5 mRNA was detectable by P1/3(607bp),

M:100bp Plus DNA ladder from Transgen (BM311). The heterozygous KI mouse expresses both human CCR5 and mouse Ccr5 in the spleen.

Related Strains

Product

Product Catalog

Background

hIL3(NMG)

NM-NSG-007

NOD

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huHSC-(NMG)

NM-NSG-017

huHSC

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R26-CAG-LSL-hFCGR2A-IRES-EGFP

NM-KI-200229

C57BL/6Smoc

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R26-CAG-LSL-hFCGR3A-IRES-tdTomato

NM-KI-200255

C57BL/6Smoc

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R26-CAG-LSL-hSOS-F-tdTomato

NM-KI-200020

C57BL/6Smoc

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hTNFRSF10C

NM-HU-230344

C57BL/6Smoc

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R26-CAG-LSL-hMLL-AF9-IRES-Luc-2A-tdTomato

NM-KI-190114

C57BL/6Smoc

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hANGPTL3(3)

NM-HU-210037

C57BL/6Smoc

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hTIM4

NM-HU-225042

C57BL/6Smoc

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hFCGR1A

NM-HU-2000072

C57BL/6Smoc

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