Pdyn-IRES-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200089

Strain Name : C57BL/6Smoc-Pdynem1(IRES-iCre)Smoc

Gene Summary

Gene Name

Model Description

A IRES-iCre expression cassette was knocked into the Pdyn gene stop codon site. Pdyn encodes prodynorphin. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying depression, stress, anxiety, pain response, circadian rhythm and appetite control.

Validation Data

image.png

Fig. 1 Cre-mediated recombination in the brain of PdynCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the cortex, hippocampus and striatum of PdynCre/+; Rosa26tdTomato/+ mouse.

image.png

Fig. 2 Detection of tdTomato(red) in various tissues of  PdynCre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in some cells of the brain, kidney, pancreas islet, heart, liver, lung, stomach, brown fat, intestine, colon, ovary, thymus and spleen. Tdtomato expression can not be observed in the salivary gland, skin or muscle. (For more detailed information please contact our technical advisor.)


Related Strains

Product
Product Catalog
Background
NM-KI-200042
C57BL/6Smoc
Inquire
NM-KI-00047
C57BL/6Smoc
Inquire
NM-KI-200148
C57BL/6Smoc
Inquire
NM-TG-220234
C57BL/6Smoc
Inquire
NM-KI-00133
C57BL/6Smoc
Inquire
NM-KI-240477
C57BL/6Smoc
Inquire
NM-KI-240492
C57BL/6Smoc
Inquire
NM-KI-240469
C57BL/6Smoc
Inquire
NM-KI-240468
C57BL/6Smoc
Inquire
NM-KI-240472
C57BL/6Smoc
Inquire
Email Back to top