Isl1-Cre

Background : C57BL/6Smoc

Catalog : NM-KI-200126

Strain Name : C57BL/6Smoc-Isl1em1(iCre-WPRE-pA)Smoc

Gene Summary

Gene Name

Model Description

A iCre-WPRE-pA expression cassette was knocked into the Isl1 gene start codon site.

Validation Data

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Fig. 1 Cre-mediated recombination in the retina of IslCreERT2 /+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the retinal ganglion cell layer (RGC) and inner nuclear layer (INL) of IslCre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Cre-mediated recombination in the pancreas of IslCre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the acinar cells and islet cells derived from IslCre/+; Rosa26tdTomato/+ mouse.

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Fig. 3 Detection of tdTomato(red) in various tissues of IslCre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the retina, pancreas, heart, brain, pituitary gland, lung, liver, stomach, submandibular gland, brown fat, kidney, intestine, colon, spleen, thymus, testis and epididymis. (For more detailed information please contact our technical advisor.)


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