Foxp3-IRES-DTR-2A-tdTomato(BALB/c)

CT 26 tumor cells were injected into FOXP3-DTR mice administered with different treatment, and Balb/c mice, respectively. And tumor growth curves of each group were recorded.

Fig 1. The growth of CT26 tumors in Foxp3-IRES-DTR-2A-tdTomato mice administered with different treatment and Balb/c mice. (In collaboration with CrownBio)

Proportion of different type-specific T cells and macrophages in peripheral blood of each group analyzed using FACS

Fig 2. The percentage of different type-specific T cells and macrophages in peripheral blood of CT26 tumor-bearing Foxp3-IRES-DTR-2A-tdTomato mice administered with different treatment and Balb/c mice is detected by FACS. (In collaboration with CrownBio)

Proportion of different type-specific T cells and macrophages in spleen and tumor of each group analyzed using FACS

Fig 3. The percentage of different type-specific T cells and macrophages in spleen and tumor of of CT26 tumor-bearing Foxp3-IRES-DTR-2A-tdTomato mice administered with different treatment and Balb/c mice is detected by FACS. (In collaboration with CrownBio)

Fig 4. DTR  mediated cell knockout  in spleen of Foxp3-DTR/tdTomato mice (BALB/c).

Fig 5. DTR  mediated cell knockout  in mesenteric lymph nodes of Foxp3-DTR/tdTomato mice(BALB/c).