hCCL5

Background : C57BL/6Smoc

Catalog : NM-HU-210014

Strain Name :

C57BL/6Smoc-CCL5tm1(hCCL5)/Smoc

Gene Summary

Gene Name
  • Synonyms :

    S, RA, Scy, MuRa, SISd, Scya5, TCP22, RANTES, TCP228, MuRantes

  • NCBI ID :

    20304

  • MGI ID :

    98262

  • Ensembl ID :

    ENSMUSG00000035042

  • Strain State :

    下架

Model Description

The endogenous mice Ccl5 gene was replaced by human CCL5 gene.

Validation Data

image.png

Fig1. Detection of CCL5 expression in small intestine by RT-PCR. 

Wild type: only one band at 242 bp with primers F1/R1(mCcl5);

Heterozygous: one band at 242 bp with primers F1/R1(mCcl5) and one band at 217 bp with primers F2/R2(hCCL5); 

Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of hCCL5 and mCCL5 expression in serum by ELISA (n=2). 

Abbr. HE, heterozygous; WT, wild type.

Note. hCCL5 and C57BL/6 mice were i.p. injected with LPS for 3h.

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