U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Cd24atm1(hCD24)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000060
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd24aem1(hCD24-flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-231034
Mice
Strain Name:C57BL/6Smoc-Cd24atm1(hCD24)Siglecgtm1(hSIGLEC10)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210367
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Cd248em1(hCD248)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225028
Mice
Strain Name:C57BL/6Smoc-Cd27tm3(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190035
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Cd27tm3(hCD27)Fcgrt2bem2(hFCGRT2B)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210405
Research Application:inmmue therapy; drug screening
Mice
Strain Name:BALB/cAnSmoc-Cd27tm(hCD27)Pdcd1em(hPD-1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220339
Mice
Strain Name:BALB/cAnSmoc-Cd27tm(hCD27)Cd274em(hPD-L1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220340
Mice
Strain Name:C57BL/6Smoc-Cd28em2(hCD28)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190011
Research Application:Immune-related
Mice
Strain Name:BALB/cAnSmoc-Cd28em(hCD28)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220509
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