U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Csf2rbtm(hCSF2RB)Il3tm(hIL3)Csf2tm(hCSF2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230239
Mice
Strain Name:NOD-PrkdcscidIl2rgem1Gt(ROSA)26Sorem1(SA-LSL-hCSF3)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-232692
Mice
Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4) Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00014
Research Application:cancer research,Immunotherapy,drug screening;
Mice
Strain Name:C57BL/6Smoc-Ctla4em2(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190038
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:BALB/cAnSmoc-Ctla4em1(hCTLA4) Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190078
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18020
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4)Cd8aem1(V5-IRES-luc-2A-EGFP)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210374
Mice
Strain Name:C57BL/6Smoc-Ctla4em1(hCTLA4)Tnfrsf9tm2(TNFRSF9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210355
Research Application:inmmue therapy;drug screening
Mice
Strain Name:BALB/cAnSmoc-Ccr8em1(hCCR8)Ctla4em1(hCTLA4)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220050
Mice
Strain Name:BALB/cAnSmoc-Ctla4em1(hCTLA4)Ccr8em(hCCR8)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234064
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