U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Cxcr6em(hCXCR6)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215001
Mice
Strain Name:C57BL/6Smoc-Cyp27a1em1(hCYP27A1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232853
Mice
Strain Name:C57BL/6Smoc-Cyp2dtm(hCYP2D)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215016
Mice
Strain Name:C57BL/6Smoc-Cyp2dtm(hCYP2D6)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-215024
Mice
Strain Name:C57BL/6Smoc-Ddr1tm1(hDDR1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225086
Mice
Strain Name:C57BL/6Smoc-Dgat2tm1(hDGAT2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-233515
Mice
Strain Name:C57BL/6Smoc-Dkk1em1(hDKK1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234202
Mice
Strain Name:C57BL/6Smoc-Dlk1tm1(hDLK1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234369
Mice
Strain Name:C57BL/6Smoc-Dll3em1(hDLL3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200231
Mice
Strain Name:C57BL/6Smoc-Dll4tm1(hDLL4)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000020
Research Application:Immunotherapy,drug screening
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