U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Adora2atm1(hADORA2A)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215061
Mice
Strain Name:BALB/cAnSmoc-Adora2atm1(hADORA2A)Smoc
Strain State:Developing | Cat. NO.:NM-HU-232255
Mice
Strain Name:C57BL/6Smoc-Adora2btm(hADORA2B)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220424
Mice
Strain Name:C57BL/6Smoc-Agttm1(hAGT)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225082
Mice
Strain Name:C57BL/6Smoc-Tg(hAGT)1Smoc
Strain State:Developing | Cat. NO.:NM-TG-230035
Mice
Strain Name:C57BL/6JSmoc-Agttm1(hAGT)Ren1em(hREN)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234349
Mice
Strain Name:C57BL/6Smoc-Ahrem1(hAHR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200252
Mice
Strain Name:C57BL/6Smoc-Albem3(ALB)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200003
Research Application:Drug screening
Mice
Strain Name:C57BL/6Smoc-Albem3(hALB)Fcgrtem2(hFCGRT)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200278
Mice
Strain Name:C57BL/6Smoc-Aldh2tm1(hALDH2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-231912
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