U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Amhr2em1(hAMHR2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-234372
Mice
Strain Name:C57BL/6Smoc-Angpt2tm1(hANGPT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200247
Mice
Strain Name:C57BL/6Smoc-Angptl3em2(hANGPTL3)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-210037
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Angptl3em1(hANGPTL3)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210036
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Angptl3tm2(hANGPTL3)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230047
Mice
Strain Name:C57BL/6Smoc-Angptl4tm(hANGPTL4)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220285
Mice
Strain Name:C57BL/6Smoc-Apobtm1(hAPOB)Smoc
Strain State:Developing | Cat. NO.:NM-HU-231780
Mice
Strain Name:C57BL/6Smoc-Apobtm2(hAPOB)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-231781
Mice
Strain Name:C57BL/6Smoc-Apoc3em1(hAPOC3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225050
Mice
Strain Name:C57BL/6Smoc-Apoetm4(hAPOE2)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190013
Research Application:Immune-related
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