U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200275
Mice
Strain Name:BALB/cAnSmoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220018
Mice
Strain Name:C57BL/6Smoc-Il2tm3(hIL2)Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210415
Mice
Strain Name:C57BL/6Smoc-Il2rgem1(IL2RG)Il2tm3(hIL2)Il2rbtm1(hIL2RB)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220145
Mice
Strain Name:C57BL/6Smoc-Il21tm1(hIL21)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200255
Mice
Strain Name:C57BL/6Smoc-Il21tm1(hIL21)Il21rtm1(hIL21R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220038
Mice
Strain Name:C57BL/6Smoc-Il21rtm1(hIL21R)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210031
Research Application:inmmue therapy;drug screening
Mice
Strain Name:C57BL/6Smoc-Il21rtm1(hIL21R)Il2rgem1(IL2RG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220004
Mice
Strain Name:C57BL/6Smoc-Il22tm(hIL22)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-220419
Mice
Strain Name:C57BL/6Smoc-Il23aem3(hIL23A)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-18030
Research Application:Immunotherapy,Cancer research,Drug screening
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