U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:BALB/cAnSmoc-Il23aem3(hIL23A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220013
Mice
Strain Name:C57BL/6Smoc-Il23aem3(hIL23A)Il12btm3(hIL12B)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-233778
Mice
Strain Name:C57BL/6Smoc-Il2ratm1(hIL2RA)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190064
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Il2ratm1(hIL2RA)Ccr8em1(hCCR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220096
Mice
Strain Name:C57BL/6Smoc-Il2ratm1(hIL2RA)Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210414
Mice
Strain Name:C57BL/6Smoc-Il2rgem1(IL2RG)Il2ratm1(hIL2RA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220144
Mice
Strain Name:C57BL/6Smoc-Il2rbtm1(hIL2RB)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000055
Research Application:Cytokine humanization model;drug screening
Mice
Strain Name:C57BL/6Smoc-Il2rbtm1(hIL2RB)Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-220036
Mice
Strain Name:C57BL/6Smoc-Il2rgem1(IL2RG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200007
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Il2rgem1(IL2RG)Il2rbtm1(hIL2RB)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210354
Research Application:inmmue therapy;drug screening
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