U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Notch3tm(hNOTCH3)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230037
Mice
Strain Name:C57BL/6Smoc-Npm1tm1(hNPM1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230146
Mice
Strain Name:C57BL/6Smoc-Npr3tm1(hNPR3)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234682
Mice
Strain Name:C57BL/6Smoc-Nr1h2em1(hNR1H2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234706
Mice
Strain Name:C57BL/6Smoc-Nr1i2em3(hNR1I2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000066
Research Application:Pharmacokinetic-related model
Mice
Strain Name:C57BL/6Smoc-Nr1i3tm1(hNR1I3)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200253
Mice
Strain Name:C57BL/6Smoc-Nr3c1tm1(hNR3C1)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-225058
Mice
Strain Name:C57BL/6Smoc-Nrp1tm1(hNRP1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225046
Mice
Strain Name:C57BL/6Smoc-Ntrk1em(hNTRK1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230058
Mice
Strain Name:C57BL/6Smoc-Ntrk2tm(hNTRK2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230060
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