U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Parp14tm1(hPARP14)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234703
Mice
Strain Name:C57BL/6Smoc-Pcsk9em2(hPCSK9)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00075
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pcsk9tm2(hPCSK9)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230151
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-00015
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1tm1(hPDCD1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-235087
Mice
Strain Name:BALB/cAnSmoc-Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190079
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd8aem1(V5-IRES-Akaluc-2A-EGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210373
Mice
Strain Name:BALB/cAnSmoc-Pdcd1em1(hPDCD1)Ccr8em(hCCR8)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234063
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd27tm2(hCD27)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000096
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd28em2(hCD28)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-2000097
Research Application:Immunotherapy,cancer research,drug screening
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