U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:BALB/cAnSmoc-tmem173tm1(htmem173)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000049
Research Application:Immunotherapy,drug screening
Mice
Strain Name:C57BL/6Smoc-Stk25tm1(hSTK25)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-232135
Mice
Strain Name:C57BL/6Smoc-Tnfrsf13btm1(hTNFRSF13B)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234511
Mice
Strain Name:C57BL/6Smoc-Tardbptm(hTARDBP)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230026
Mice
Strain Name:C57BL/6Smoc-Tgtn(pPrp-hTDP-43 A315T)1Smoc
Strain State:Developing | Cat. NO.:NM-KI-234659
Mice
Strain Name:C57BL/6Smoc-Tfrctm1(hTFRC)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-215059
Mice
Strain Name:C57BL/6Smoc-Tfrctm(hTFRC)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-HU-230029
Mice
Strain Name:C57BL/6Smoc-Tgfb1tm1(hTGFB1)Smoc
Strain State:Developing | Cat. NO.:NM-HU-200243
Mice
Strain Name:C57BL/6Smoc-Tgfbr2tm(hTGFBR2)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230041
Mice
Strain Name:C57BL/6Smoc-Thpotm1(hTHPO)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000062
Research Application:Cytokine humanization model;drug screening
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