U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:BALB/cAnSmoc-Thpotm1(hTHPO)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-234937
Mice
Strain Name:NOD-PrkdcscidIl2rgem1Thpotm(hTHPO)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220429
Mice
Strain Name:C57BL/6Smoc-Thpotm1(hTHPO)Sirpatm2(hSIRPA)Smoc
Strain State:Developing | Cat. NO.:NM-XA-234931
Mice
Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-00053
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Tigittm3(hTIGIT)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200244
Mice
Strain Name:BALB/cAnSmoc-Tigittm4(hTIGIT)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-200245
Mice
Strain Name:C.B6-Tigittm3(hTIGIT)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234664
Mice
Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Ccr8em1(hCCR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210426
Mice
Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Pvrem1(hPVR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000091
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Tigittm3(hTIGIT)Tnfrsf1bem2(hTNFRSF1B)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-210371
Research Application:inmmue therapy;drug screening
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