U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Tlr7tm1(hTLR7)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18027
Research Application:Immunotherapy,Cancer research,Drug screening
Mice
Strain Name:C57BL/6Smoc-Tlr8tm2(TLR8)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-190044
Research Application:Immunotherapy,cancer research,drug screening
Mice
Strain Name:C57BL/6Smoc-Tlr8tm2(TLR8)Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200276
Mice
Strain Name:C57BL/6Smoc-Lyz2em3(IRES-DTREGFP)Tlr8tm2(TLR8)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200259
Research Application:tumor research;inmmue therapy;drug screening;myeloid cell-specific DTR mice
Mice
Strain Name:C57BL/6Smoc-Tlr9tm1(hTLR9)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-18016
Research Application:drug screening
Mice
Strain Name:C57BL/6Smoc-Tlr9tm1(hTLR9)Tnfrsf4em3(hTNFRSF4)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190024
Research Application:Immune-related
Mice
Strain Name:C57BL/6Smoc-tm4sf1tm(htm4SF1)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-230066
Mice
Strain Name:C57BL/6Smoc-Tnctm(hTNC)Smoc
Strain State:Developing | Cat. NO.:NM-HU-230025
Mice
Strain Name:C57BL/6Smoc-Tgtn(hTNF-β-globin)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-TG-233181
Mice
Strain Name:C57BL/6Smoc-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-TG-200004
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