U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Tnfrsf1aem(hTNFRSF1A)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-215017
Mice
Strain Name:C57BL/6Smoc-Tnfrsf8tm(hTNFRSF8)Smoc
Strain State:Developing | Cat. NO.:NM-HU-220202
Mice
Strain Name:C57BL/6Smoc-Tnfsf11tm1(hTNFSF11)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234270
Mice
Strain Name:C57BL/6Smoc-Tnfsf13btm1(hTNFSF13B)Smoc
Strain State:Developing | Cat. NO.:NM-HU-240330
Mice
Strain Name:C57BL/6Smoc-Tnfsf14tm1(hTNFSF14)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-225069
Mice
Strain Name:C57BL/6Smoc-Trp53tm1(hTP53)Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-225052
Mice
Strain Name:C57BL/6Smoc-Tp53em1(hTP53-R175H)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234694
Mice
Strain Name:C57BL/6Smoc-Tp53em2(hTP53-R273H)Smoc
Strain State:Developing | Cat. NO.:NM-HU-234695
Mice
Strain Name:C57BL/6Smoc-Tpbgem1(hTPBG)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200239
Mice
Strain Name:C57BL/6Smoc-Trem2em4(hTRem2)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000083
Research Application:Alzheimer's disease research;drug screening
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