U-GEMMs

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-FRT-2xpolyA-CAG-FRT-Loxp-stop-loxp-human ACE2-IRES-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200188
Research Application:corona virus related research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(R26-CAG-Loxp-Stop-Loxp-hAR-IRES-EGFP-WPRE-pA)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-215053
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-loxp-STOP-loxp-BCR-ABL-IRES-Luciferase-2A-tdTomato-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190127
Research Application:Chronic Myelocytic Leukemia(CML) research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hCD2 C truncated-WPRE-polyA)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-200321
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(pCAG-FRT-loxp-stop-loxp-hCD63-copGFP-6xHis-WPRE-polyA-FRT)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-200044
Research Application:Exosome tracing model
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-hDSG2-WPRE-pA)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-210444
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (L858R)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190069
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (L858R-T790M)-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-190068
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (L858R-T790M-C797S)-IRES-luciferase-2A-tdTomato)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-190067
Research Application:cancer research
Mice
Strain Name:C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-EGFR (T790M) -IRES-Luciferase-2A-tdTomato)Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-190070
Research Application:cancer research
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