SMOC has developed a set of mouse models expressing humanized immune checkpoints. These models are suitable to assess the efficacy of drugs targeting immune checkpoints in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Icoslem1(hICOSLG) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00095
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Icosltm3(hICOSLG)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000068
Research Application：Immunotherapy,drug screening
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Strain Name：B6;129S-Ido1tm1(hIDO1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00061
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：C57BL/6Smoc-Il1rl1tm4(hIL1RL1)Il4tm3(hIL4)Il4ratm1(hIL4R)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-232112
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Strain Name：C57BL/6Smoc-Il2rbtm1(hIL2RB)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220036
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Strain Name：C57BL/6Smoc-Il3tm1(hIL3)Csf2tm1(CSF2)Sirpatm2(hSIRPA)Cd47em1(hCD47)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200270
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Strain Name：C57BL/6Smoc-Tgtn(hKIR3DL3)1Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-220605
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Strain Name：C57BL/6Smoc-Klrk1em1(hKLRK1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190005
Research Application：Immune-related
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Strain Name：B6.129S-Lag3tm1(hLAG3)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-00049
Research Application：Immunotherapy,cancer research,drug screening
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Strain Name：BALB/cAnSmoc-Lag3em1(hLAG3)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000051
Research Application：Immunotherapy,drug screening
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