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U-GEMMs

About 42,406 results
Mice

hCD40/hPD-1/hPD-L1

Strain Name：C57BL/6Smoc-Cd40em1(hCD40)Pdcd1em1(hPDCD1)Cd274em1(hPD-L1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210406

hPD-1/hPD-L1(NM-HU-00100) was crossed with hCD40（NM-HU-00076）to generate hCD40/hPD-1/hPD-L1 mice

Mice

Il1a-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il1aem1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00009

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. According to this strategy, the endogenous Il1a expression is supposed to be eliminated and the intrisic promoter drives the expression of reporter genes, which reflexs the activity of Il1a.

Mice

hIl5

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190001

This IL5 humanized mouse model was established by replacing the mouse Il5 gene coding exons and introns with the human TLR9 corresponding sequence by homologous recombination.

Mice

hIL1RL1

Strain Name：C57BL/6Smoc-Il1rl1tm4(hIL1RL1)/Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-2000067

The endogenous mouse Il1rl1 gene was replaced by human IL1RL1 gene.

Mice

Il15-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il15em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00027

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il15.

Mice

Eno2-2A-CreERT2

Strain Name：C57BL/6Smoc-Eno2em1(2A-CreERT2)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200011

A 2A-CreERT2 expression cassette was knocked into the Eno2 gene stop codon site.

Mice

Slc6a1-S295L

Strain Name：C57BL/6Smoc-Slc6a1em2(S295L)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190014

These mice carry a p.S295L mutation in Slc6a1 gene .

Mice

hHLA-A11

Strain Name：C57BL/6Smoc-H2-K1tm1(hHLA-A11)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-204987

The endogenous mice H2-K1 gene was replaced by human HLA-A11 gene.

Mice

hCD3E/hSDC1

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Sdc1em1(hSDC1)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220021

hCD3E(NM-HU-00114) was crossed with hSDC1(NM-HU-2000026) to generate hCD3E/hSDC1 mice.

Mice

Fah-KO

Strain Name：C57BL/6Smoc-Fahem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-191202

Partial exon 8 of Fah gene was deleted to generate Fah knockout mice.

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