Therapeutic Target-Humanized Mice
Cre/Dre-Driver Mice
Strain Name：C57BL/6Smoc-Pdcd1lg2em1(hPDCD1LG2)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190050
将小鼠Pdcd1lg2基因全部或者部分替换为人源PDCD1LG2，从而表达人或人鼠嵌合PDCD1LG2蛋白，取代小鼠内源Pdcd1lg2蛋白的表达 hPD-L2.
Strain Name：NOD-PrkdcscidIl2rgem1Kitlem1(hKITLG)/Smoc Strain State：Developing | Cat. NO.：NM-HU-2000039
The endogenous mouse Kitl gene was replaced by human KITLG gene.
Strain Name：C57BL/6Smoc-Zp3em(2A-Cre-WPRE-pA)1Smoc Strain State：Repository Live | Cat. NO.：NM-KI-225029
2A-Cre-WPRE-pA expression cassette was knocked into the Zp3 gene .
Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-Luc-EGFP)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-00087
This R26-(CAG-Luc-EGFP) strain was generated by crossing R26-(CAG-LSL-Luc-EGFP)(NM-KI-190095) mice with Ddx4-Cre mice.
Strain Name：C57BL/6Smoc-Il21tm1(hIL21)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200255
The endogenous mice Il21 gene was replaced by human IL21 gene.
Strain Name：C57BL/6Smoc-Cd180em1(hCD180)/Smoc Strain State：Repository Live | Cat. NO.：NM-HU-210006
The endogenous mice Cd180 gene was replaced by human CD180 gene
Strain Name：C57BL/6Smoc-Igs2em1(CAG-LSL-HAtag-Mycn-IRES-EGFP)Smoc Strain State：Repository Live | Cat. NO.：NM-KI-190084
These mice harbor a CAG-LSL-HA tag-Mycn-IRES-EGFP cassette in the lgs2 locus generated by homologous recombination.
Strain Name：C57BL/6Smoc-Krt5em1(2A-CreERT2)Smoc Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-190016
The 2A-CreERT2 cassette is inserted before 3'UTR region of Krt5 gene.
Strain Name：C57BL/6Smoc-Wdfy1em(Kozak-CreERT2-WPRE-pA )Smoc Strain State：Repository Live | Cat. NO.：NM-KI-220121
Kozak-CreERT2-WPRE-pA expression cassette was knocked into the Wdfy1 gene start codon site.
Strain Name：C57BL/6Smoc-Pdcd1em1(hPDCD1)Cd3eem1(hCD3E)Smoc Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18021
hPD-1（NM-HU-00015）was crossed with hCD3E（NM-HU-00114）to generate hPD-1/hCD3E。
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