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U-GEMMs

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Mice

hCD3E/hPD-L1

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E)Cd274em1(hPD-L1)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-210449

hCD3E(NM-HU-00114) was crossed with hPD-L1(NM-HU-00062) to generate hCD3E/hPD-L1 mice

Mice

Cd200-KO

Strain Name：C57BL/6Smoc-Cd200em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-190029

This Cd200 knockout mouse model was generated by knocking out the exon 2 region of the Cd200 .

Mice

hIL5/hIL5R(3)

Strain Name：C57BL/6Smoc-Il5tm3(hIL5)Il5raem3(hIL5RA)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-220011

The endogenous mouse Il5 and Il5ra genes was replaced by human IL5 and IL5ra genes. While hIL5/hIL5R(Stock No.NM-HU-2000101) mice and hIL5/hIL5R(2)(Stock No.NM-HU-220010) function similarly to hIL5/hIL5R(3) mice, for more detailed information please contact our technical advisor.

Mice

R26-CAG-LSL-hTARDBP*A315T-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200019

These mice harbor a CAG-LSL-3xFlag-TARDBP(A315T)-IRES-GFP-WPRE-PA cassette in the Rosa26 locus generated by homologous recombination.

Mice

Isl1-CreERT2

Strain Name：C57BL/6Smoc-Isl1em1(CreERT2) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00013

CreERT2 was inserted at the start codon (ATG site). The KI mice have a tamoxifen-inducible cre-mediated recombination system.

Mice

hEPCAM

Strain Name：C57BL/6Smoc-EpCAMtm1(hEpCAM)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-210032

The endogenous mice Epcam gene was completely or partially replaced by human EPCAM gene via ESC targeting.

Mice

A1bg-Flox

Strain Name：C57BL/6Smoc-A1bgem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A1bg gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A1bg gene.

Mice

Slc6a1-KO

Strain Name：B6;129S-Slc6a1tm1Smoc
Strain State：Repository Live | Cat. NO.：NM-KO-00002

Slc6a1-KO mice(Stock No.NM-KO-00002）carry a knockout allele derived from the targeted deletion of exon 2-3. While Slc6a1-KO(2) mice (Stock No.NM-KO-210290）carrying the exon 6 deletion. Slc6a1-KO(3) mice(Stock No.NM-KO-210126） carrying the exon 7 deletion.

Mice

hIL23A

Strain Name：C57BL/6Smoc-Il23aem3(hIL23A)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-18030

The endogenous mouse Il23a gene was replaced by humanIL23A gene .

Mice

A2m-Flox

Strain Name：C57BL/6Smoc-A2mem1(flox)Smoc
Strain State：Developing | Cat. NO.：TBD

These mice carry loxP sites flanking target exons of A2m gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of A2m gene.

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