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U-GEMMs

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Mice

Akt2-KO

Strain Name:C57BL/6Smoc-Akt2em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-190742

Exon 3-4 of Akt2 gene was deleted to generate Akt2 knockout mice.

Mice

hCD40/hCD40L

Strain Name:C57BL/6Smoc-CD40em2(hCD40)Cd40lgtm1(hCD40L)/Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-200268

hCD40(NM-HU-00076)was crossed with hCD40L(NM-HU-2000033)to generate hCD40/hCD40L mice

Mice

hNECTIN4

Strain Name:C57BL/6Smoc-Nectin4tm1(hNECTIN4)/Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-210016

The endogenous mice Nectin4 gene was replaced by human NECTIN4 gene.

Mice

Il12a-Luc-2A-EGFP

Strain Name:C57BL/6Smoc-Il12aem1(Luc-eGFP)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KI-00024

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il12a.

Mice

Ly6g-2A-CreERT2

Strain Name:C57BL/6Smoc-Ly6gem3(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200218

A 2A-CreERT2 expression cassette was knocked into the Ly6g gene start codon site.

Mice

Cd8a-2A-tdTomato-2A-Luc

Strain Name:C57BL/6Smoc-Cd8aem(T2A-tdTomato-P2A-Luciferase)1Smoc
Strain State:Sperm cryopreservation | Cat. NO.:NM-KI-225025

T2A-tdTomato-P2A-Luciferase expression cassette was knocked into the Cd8a gene .

Mice

Foxl1-2A-CreERT2

Strain Name:C57BL/6Smoc-Foxl1em1(2A-CreERT2)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-00135

A 2A-CreERT2 coexpression cassette is inserted before the stop codon of mouse Foxl1 gene via homologous recombination to establish a Foxl1-CreERT2 recombinase tool stain. This strain can be used to knockout target gene inFoxl1+ cells after tamoxifen treatment when crossed with flox mice.

Mice

A1bg-KO

Strain Name:C57BL/6Smoc-A1bgem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200806

Exon 1-5 of A1bg gene was deleted to generate A1bg knockout mice.

Mice

hIL4RA

Strain Name:C57BL/6Smoc-Il4ratm1(hIL4R)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-190008

The endogenous mouse Il4ra gene was replaced by human IL4R gene.

Mice

Calca-Cre

Strain Name:C57BL/6Smoc-Calcaem1(iCre-2A)Smoc
Strain State:Repository Live | Cat. NO.:NM-KI-200302

iCre-2A expression cassette was knocked into the Calca gene start codon site.

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