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U-GEMMs

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Mice

R26-LSL-hIL15-Flag-IRES-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220130

CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA expression cassette was knocked into the the Rosa26 locus

Mice

hTREM2

Strain Name：C57BL/6Smoc-Trem2em4(hTRem2)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-2000083

The endogenous mouse Trem2 gene was replaced by human TREM2 gene.

Mice

hPD-L1/hCD40

Strain Name：C57BL/6Smoc-Cd274em1(hPD-L1)Cd40em1(hCD40)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-18024

hPD-L1(NM-HU-00062) was crossed with hCD40(NM-HU-00076) to generate hPD-L1/hCD40.

Mice

Il18-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il18em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00032

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il18.

Mice

Emx1-IRES-Cre

Strain Name：C57BL/6Smoc-emx1em1(IRES-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200149

A IRES-Cre expression cassette was knocked into the Emx1 gene stop codon site.

Mice

Il9-Luc-2A-EGFP

Strain Name：C57BL/6Smoc-Il9em1(Luc-eGFP)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-00023

A Luciferase-2A-EGFP-pA cassette was inserted after ATG the start codon. The intrisic promoter drives the expression of reporter genes, which reflects the activity of Il9.

Mice

hCD3E/hCD38(2)

Strain Name：C57BL/6Smoc-Cd3eem1(hCD3E))Cd38em2(hCD38)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210234

hCD3E(NM-HU-00114) was crossed with hCD38(2)(NM-HU-190059) to generate hCD3E/hCD38(2) mice.

Mice

hTLR8/hPD-1

Strain Name：C57BL/6Smoc-Tlr8tm2(TLR8)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200276

hTLR8(NM-HU-190044) was crossed with hPD-1(NM-HU-00015)to generate hTLR8/hPD-1 mice

Mice

hVEGFR2

Strain Name：C57BL/6Smoc-Kdrtm2(hKDR) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00098

The endogenous mouse Kdr gene was replaced by human KDR gene .

Mice

hPCSK9

Strain Name：C57BL/6Smoc-Pcsk9em2(hPCSK9)/Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-00075

The endogenous mouse Pcsk9 gene was replaced by human PCSK9 gene .

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