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U-GEMMs

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Mice

Lat-Y136F

Strain Name：C57BL/6Smoc-Latem1(Y136F）Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200249

These mice carry a p.Y136F mutation of Lat gene.

Mice

hICOS(2)

Strain Name：C57BL/6Smoc-Icosem2(hICOS)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-190030

The endogenous mouse Icos gene was replaced by human ICOS gene. While hICOS(Stock No.NM-HU-00052) mice function similarly to hICOS(2) mice,for more detailed information please contact our technical advisor.

Mice

hFGL1

Strain Name：C57BL/6Smoc-Fgl1em1(hFGL1)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-225038

The endogenous mouse Fgl1 gene was replaced by human FGL1 gene.

Mice

Nos1-IRES-Cre

Strain Name：C57BL/6Smoc-Nos1em1(IRES-iCre)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200113

A IRES-iCre expression cassette was knocked into the Nos1 gene stop codon site.

Mice

Nipbl-Flox

Strain Name：B6;129S-Nipbltm1(flox)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-CKO-00067

An frt-neo-frt cassette was inserted after exon 5 and a loxP sites was putted before exons 5 and after the neo cassette. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of

Mice

hIL13(BALB/c)

Strain Name：BALB/cAnSmoc-Il13em2(hIL13)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220019

The endogenous mouse Il13 gene was replaced by human IL13 gene.

Mice

hIL2RG

Strain Name：C57BL/6Smoc-Il2rgem1(IL2RG)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200007

The endogenous mouse Il2rg gene was replaced by human IL2RG gene.

Mice

hTIGIT(BALB/c,2)

Strain Name：BALB/cAnSmoc-Tigittm4(hTIGIT)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-200245

The endogenous mice Tigit gene was replaced by human TIGIT gene.While hTIGIT(BALB/c) (Stock No.NM-HU-2000043) have been pulled from shelves for some reasons.

Mice

Ncr1-IRES-Cre

Strain Name：C57BL/6Smoc-Ncr1em(IRES-Cre)1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-225008

IRES-Cre expression cassette was knocked into the Ncr1 gene .

Mice

Calb1-2A-GFPCre

Strain Name：C57BL/6Smoc-Calb1em1(2A-EGFP-Cre)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200141

A 2A-EGFP-Cre expression cassette was knocked into the Calb1 gene stop codon site. Calb1 is highly expressed in the brain. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful in studying many neurobehavioral diseases such as spatial learning and circadian rhythm interference. It has been reported that the incidence of many diseases may be different between genders.

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