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U-GEMMs

About 42,406 results
Mice

hIL1B(BALB/c)

Strain Name：BALB/cAnSmoc-Il1btm3(hIL1B)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220017

The endogenous mouse Il1b gene was replaced by human IL1B gene.

Mice

NOD SCID

Strain Name：NOD.Cg-Prkdcscid/NifdcSmoc
Strain State：Repository Live | Cat. NO.：SM-019

The scid mutation has been transferred onto a diabetes-susceptible Non-Obese Diabetic (NOD) background. NOD-Scid mice do not develop diabetes, lack T and B cells, and are inherently immune deficient, making them good recipients for transplantation of human hematopoietic stem cells and human solid tumors. 

Mice

R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190075

These mice harbor a CAG-LSL-IDH2(R140Q)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

Mice

MHC ClassII(I-A/I-E)-KO(NMG)

Strain Name：NOD-PrkdcscidIl2rgem1H2-Ab1em1H2-Aaem1H2-Eb1em1H2-Eb2em1H2-Ea-ps em1Smoc
Strain State：Developing | Cat. NO.：NM-NSG-003

All sequences from the upstream of  mouse H2-Ab1 gene exon 2  to the upstream of the H2-Ea-ps gene  exon 1 were knocked out to obtain H2-Ab1、H2-Aa、H2-Eb1、H2-Eb2、H2-Ea-ps knockout mouse models.  These MHC class II molecule-deficient mice were on the NMG genetic background and also lacked cell surface expression of both class II-A and class II-E MHC proteins.

Mice

hCTLA-4(BALB/c)

Strain Name：BALB/cAnSmoc-Ctla4em1(hCTLA4) Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-190078

Obtained by backcrossing of NM-HU-00014，hCTLA-4 mice.

Mice

A4galt-KO

Strain Name：C57BL/6Smoc-A4galtem1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200001

Exon 3 of A4galt gene was deleted to generate A4galt knockout mice.

Mice

hCXCR5

Strain Name：C57BL/6Smoc-Cxcr5em(hCXCR5)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-HU-215007

The endogenous mice Cxcr5 gene was replaced by human CXCR5 gene.

Mice

Adipoq-IRES-Dre

Strain Name：C57BL/6Smoc-Adipoqem(IRES-Dre)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225055

IRES-Dre expression cassette was knocked into the Adipoq gene .

Mice

Cd4-IRES-DTRGFP

Strain Name：C57BL/6Smoc-Cd4em5(IRES-DTREGFP)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190121

A IRES-DTREGFP expression cassette was knocked into the Cd4 gene stop codon site.

Mice

hSIRPA(2)/hCD47/hCTLA-4

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Ctla4em1(hCTLA4) Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210368

hCTLA4(NM-HU-00014) was crossed with hSIRPA(2)/hCD47(NM-HU-2000111）to generate hSIRPA(2)/hCD47/hCTLA4 mice

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