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U-GEMMs

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Mice

Crbn-I391V/Rag2-KO

Strain Name：C57BL/6Smoc-Crbnem1(I391V)Rag2em2Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-210398

Crbn-I391V(NM-KI-200331) was crossed with Rag2-KO(NM-KO-190429) to generate Crbn-I391V/Rag2-KO mice.

Mice

hTIGIT/hCCR8

Strain Name：C57BL/6Smoc-Tigitem1(hTIGIT)Ccr8em1(hCCR8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-210426

hTIGIT(NM-HU-00053) was crossed with hCCR8(NM-HU-190053) to generate hTIGIT/hCCR8 mice.

Mice

hNKG2A/hCD94

Strain Name：C57BL/6Smoc-Nkg2tm1(hNKG2A)Cd94tm1(hCD94)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000016

The endogenous mouse Nkg2 and Cd94 gene was replaced by human NKG2A and CD94 gene.

Mice

Tff1-Cre

Strain Name：C57BL/6Smoc-Tff1em(Cre)1Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-225005

Cre expression cassette was knocked into the Tff1 gene .

Mice

hPD-1/hVISTA

Strain Name：C57BL/6Smoc-Visrem1(hVSIR)Pdcd1em1(hPDCD1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000092

hPD-1(NM-HU-00015) was crossed with hSIRPA(2) (NM-HU-18015) to generate hPD-1/hVISTA.

Mice

Abcc2-KO

Strain Name：C57BL/6Smoc-Abcc2em3Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-18017

Exon4-6 of Abcc2 gene were deleted to generate Abcc2 knockout mice.

Mice

Apc-Flox

Strain Name：C57BL/6Smoc-Apctm2(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-200013

These mice carry loxP sites flanking exon 15 of Apc gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Apc gene.

Mice

hSIGLEC8

Strain Name：C57BL/6Smoc-Sigleceem1(hSIGLEC8)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-204983

The endogenous mice Siglece gene was replaced by human SIGLEC8 gene. While hSIGLEC8(2)(Stock No.NM-HU-210033) mice function similarly to hSIGLEC8 mice,for more detailed information please contact our technical advisor.

Mice

Notch3-R170C

Strain Name：C57BL/6Smoc-Notch3em1(R170C)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-200254

These mice carry a p.R170C mutation of Notch3 gene.

Mice

R26-CAG-LSL-hIDH2*R172K-IRES-Luci-2A-tdTomato

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KI-190076

These mice harbor a CAG-LSL-IDH2(R172K)-IRES-Luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination.

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