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U-GEMMs

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Mice

hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)

Strain Name：C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47)Pdcd1em1(hPDCD1)Cd274em2(hPD-L1)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220029

hSIRPA(2)(NM-HU-18015), hCD47(NM-HU-00050) and hPD-1(NM-HU-00015) was crossed with hPD-L1(2)(NM-HU-190039）to generate hSIRPA(2)/hCD47/hPD-1/hPD-L1(2) mice.

Mice

R26-CAG-EGFP

Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem1(SA-2xpA-CAG-EGFP-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-190088

These mice harbor a SA-2xpA-CAG-EGFP-WPRE-polyA cassette in the Rosa26 locus generated by homologous recombination. While R26-CAG-EGFP(2)(Stock No.NM-KI-190089) and R26-CAG-EGFP(3)(Stock No.NM-KI-190090) function similarly to R26-CAG-EGFP mice,for more detailed information please contact our technical advisor.

Mice

Cdh6-CreERT2

Strain Name：C57BL/6Smoc-Cdh6em1(CreERT2-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200140

A CreERT2-WPRE-polyA expression cassette was knocked into the Cdh6 gene start codon site.

Mice

C57BL/6

Strain Name：C57BL/6Smoc
Strain State：Repository Live | Cat. NO.：SM-001

C57BL/6 mice have a high reproductive capacity, a long life span, and a low tumor susceptibility. Male mice are aggressive and fight frequently. Diet can cause obesity, type II diabetes, and atherosclerosis in these mice. The C57BL/6 mouse is the first to have its entire genome sequenced. It is the most extensively used inbred mouse strain as a genetic basis for congenic and mutant mice. It is also used in genetics, metabolism, immunology, neurology, behavioral research, pharmacodynamics, and medication safety evaluation.

Mice

Cdkal1-Flox

Strain Name：C57BL/6Smoc-Cdkal1em1(flox)Smoc
Strain State：Repository Live | Cat. NO.：NM-CKO-234794

These strains carry loxP sites flanking exon 5 of Cdkal1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cdkal1 gene.

Mice

hIL7(BALB/c)

Strain Name：BALB/cAnSmoc-Il7tm1(hIL7)Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-220014

The endogenous mouse Il7r gene was replaced by human IL7R gene.

Mice

Myf5-Cre

Strain Name：C57BL/6Smoc-Myf5em1(Cre-WPRE-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-200147

A Cre-WPRE-polyA expression cassette was knocked into the Myf5 gene start codon site. Myogenic factor 5 (Myf5) belongs to the MRF family transcription factors that regulate myogenesis. It is expressed in the skeletal muscle and satellite cells. Severe loss of skeletal muscle following ablation of Myf5-expressing progenitors. This strain is useful in studying the differentiation of skeletal muscle.

Mice

Ncr1-2A-CreERT2

Strain Name：C57BL/6Smoc-Ncr1em4(2A-CreERT2-WPRE-polyA)Smoc
Strain State：Repository Live | Cat. NO.：NM-KI-200004

A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ncr1 gene stop codon site.

Mice

Lepr-KO

Strain Name：C57BL/6Smoc-Leprem1Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KO-190663

Exon 5 of Lepr gene was deleted to generate Lepr knockout mice.

Mice

Aak1-KO

Strain Name：C57BL/6Smoc-Aak1em1Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-KO-200002

Exon 3 of Aak1 gene was deleted to generate Aak1 knockout mice.

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