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U-GEMMs

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Mice

Ghr-KO

Strain Name:C57BL/6Smoc-Ghrem1Smoc
Strain State:Repository Live | Cat. NO.:NM-KO-190649

Ghr-KO mice (Stock No.NM-KO-190649) carry a knockout allele derived from the targeted deletion of exon 4. While Ghr-KO(2) mice (Stock No.NM-KO-200636)mice carrying the exon 1-7 deletion.

Mice

Ube3a-KO

Strain Name:C57BL/6Smoc-Ube3aem1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200599

Exon 5 of Ube3a gene was deleted to generate Ube3a knockout mice.

Mice

Aacs-KO

Strain Name:C57BL/6Smoc-Aacsem1Smoc
Strain State:Developing | Cat. NO.:TBD

Exon 2 of Aacs gene was deleted to generate Aacs knockout mice.

Mice

Lrp1-Flox

Strain Name:C57BL/6Smoc-Lrp1em1(flox)Smoc
Strain State:Repository Live | Cat. NO.:NM-CKO-2101319

These mice carry loxP sites flanking exon 7-8 of Lrp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Lrp1 gene.

Mice

Tyro3-KO

Strain Name:C57BL/6Smoc-Tyro3em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200558

Exon 3 of Tyro3 gene was deleted to generate Tyro3 knockout mice.

Mice

Aadat-Flox

Strain Name:C57BL/6Smoc-Aadatem1(flox)Smoc
Strain State:Developing | Cat. NO.:TBD

These mice carry loxP sites flanking target exons of Aadat gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Aadat gene.

Mice

hSIRPA(2)/hCD47/hPD-1

Strain Name:C57BL/6Smoc-Sirpatm2(hSIRPA)Cd47em1(hCD47) Pdcd1em1(hPDCD1)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000090

hPD-1(NM-HU-00015),hCD47(NM-HU-00050) were crossed with hSIRPA(2) (NM-HU-18015) to generate hSIRPA(2)/hCD47/hPD-1.

Mice

hTIGIT/hPVR

Strain Name:C57BL/6Smoc-Tigitem1(hTIGIT)Pvrem1(hPVR)Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-HU-2000091

These mice are obtained through breeding of two single gene humanized mice.

Mice

hCD3EDG/hPD-L1

Strain Name:C57BL/6Smoc-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd274em1(hPD-L1) /Smoc
Strain State:Repository Live | Cat. NO.:NM-HU-220112

hCD3EDG(NM-HU-220120) mice were crossed with hPD-L1(NM-HU-00062) mice to generate hCD3EDG/hPD-L1 mice

Mice

Slc34a1-KO

Strain Name:C57BL/6Smoc-Slc34a1em1Smoc
Strain State:Embryo cryopreservation | Cat. NO.:NM-KO-200642

Exon 3-6 of Slc34a1 gene was deleted to generate Slc34a1 knockout mice.

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