Acta2-CreERT2

Background : C57BL/6Smoc

Catalog : NM-KI-200074

Strain Name : C57BL/6Smoc-Acta2em1(CreERT2-Wpre-polyA)Smoc

Gene Summary

Gene Name
  • Synonyms :

    Actvs, a-SMA, SMAalpha, SMalphaA, alphaSMA, 0610041G09Rik

  • NCBI ID :

    11475

  • MGI ID :

    87909

  • Ensembl ID :

    ENSMUSG00000035783

  • Strain State :

    活体

Model Description

A CreERT2-Wpre-polyA expression cassette was knocked into the Acta2 gene start codon site.

Validation Data

NM-KI-200074;Acta2-CreERT2-1.png

Fig. 1 CreERT2-mediated recombination in the pancreas of Acta2CreERT2 /+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the vascular smooth muscle cells of Acta2 CreERT2 /+; Rosa26tdTomato/+ mouse after tamoxifen treatment. Some leakiness were detected prior to tamoxifen exposure. 

NM-KI-200074;Acta2-CreERT2-2.png

Fig. 2 Detection of tdTomato(red) in various tissues of Acta2CreERT2/+; Rosa26tdTomato/+ mice. CreERT2 mediated recombination can be detected in the pancreas, kidney, brain, heart, lung, liver, thymus, submandibular gland, brown fat, ovary, muscle, thymus, spleen, large intestine and small intestine. Leakiness were detected in the above tissues prior to tamoxifen exposure. Tdtomato expression can not be observed in the pituitary gland. (For more detailed information please contact our technical advisor.)

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