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Home / Toolbox of Mice / Find Cre / Alb-CreERT2

Alb-CreERT2

Background : B6.129S

Catalog : NM-KI-00002

Strain Name :

B6.129S-Albtm1.1(CreERT2)Smoc

Gene Summary

Gene Name

Model Description

Exons 1-7 were replaced by CreERT2 and a loxp neo casette. The KI mice have a tamoxifen-inducible cre-mediated recombination system.This strain has removed the Neo screening gene.

Validation Data

alb-creERT2-1.png

Fig1 X-gal staining of liver slides of Alb-CreERT2 and LacZ positive mouse before and after tamoxifen injection. 

alb-creERT2-2.png

Fig2  Immunofluorescence analysis of liver using anti-Alb(Green) and anti-LacZ(Red) antibodies showed that Cre is expressed in most hepatocytes.

alb-creERT2-3.png

Fig3  Blood biochemical assay of Alb-CreERT2 male and female mice. Alb-CreERT2 mice do not display any liver functional abnormalities.

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