hAXL

Background : C57BL/6Smoc

Catalog : NM-HU-215067

Strain Name :

C57BL/6Smoc-Axltm1(hAXL)Smoc

Gene Summary

Gene Name

Model Description

The endogenous mouse Axl gene was replaced by human AXL gene.

Validation Data

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Fig1. Detection of AXL expression in lung and spleen by RT-PCR. 

Wild type: only one band at 202 bp with primers F1/R1(mAxl); Homozygous: only one band at 249 bp with primers F2/R2(hAXL). Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

image.png

Fig2. Detection of human AXL expression in liver in hAXL knockin mice by WB. 

Livers were collected from wild-type mice (+/+) and homozygous hAXL mice (HO/HO), and analyzed by western blot with anti-AXL antibody. Abbr. HO/HO, homozygous; +/+, wild type.

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