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hCD40(BALB/c)

Background : BALB/cAnSmoc

Catalog : NM-HU-2000047

Strain Name : BALB/cAnSmoc-Cd40^{em1(hCD40)/Smoc}

Gene Summary

Gene Name

Synonyms :
IGM, p50, Bp50, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936
NCBI ID :
21939
MGI ID :
88336
Ensembl ID :
ENSMUSG00000017652
Strain State :
胚胎冻存

Model Description

The endogenous mouse Cd40 gene was replaced by human CD40 gene.

Validation Data

Fig1. Analysis of hCD40 expression in PBMC in the hCD40 mice by FACS. hCD40 was expressed on B cells in PB.

Fig2. Analysis of hCD40 expression on splenic B cells by FACS. hCD40 was expressed on the B cells in the spleen.

Fig3. Analysis of human CD40 expression on splenic DCs and macrophages by FACS . The homozygous KI mouse expresses human CD40 on DCs and macrophages.（Provided by CrownBio）

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