Home / hCTLA-4/hCD28(BALB/c)

hCTLA-4/hCD28(BALB/c)

Background : BALB/cAnSmoc

Catalog : NM-HU-200226

Strain Name :

BALB/cAnSmoc-Ctla4^em1(hCTLA4)Cd28^{em1(hCD28)Smoc}

Gene Summary

Gene Name

Synonyms :
Cd152, Ly-56, Ctla-4,
NCBI ID :
12477 12487
MGI ID :
88556 88327
Ensembl ID :
ENSMUSG00000026011 ENSMUSG00000026012
Strain State :
精子冻存

Model Description

The endogenous mice Ctla4 and Cd28 gene was replaced by human CTLA4 and CD28 gene.

Validation Data

Fig1. Analysis of human CTLA4(hCD152) expression in the spleen by FACS . The homozygous KI mouse expresses human CTLA4 on T cells.

Fig2. Analysis of human CD28 expression in the spleen by FACS . The homozygous KI mouse expresses human CD28 on T cells.

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